Dose-Dependent Effects ofRunx2on Bone Development
نویسندگان
چکیده
منابع مشابه
Multiple dose-dependent effects of Lis1 on cerebral cortical development.
Humans with heterozygous inactivating mutations of the Lis1 gene display type I lissencephaly, a severe form of cortical dysplasia hypothesized to result from abnormal neuronal migration. Previously we reported the construction of an allelic series of the Lis1 gene in mice to analyze the effects of graded reduction of LIS1 protein on the pathogenesis of this disorder and demonstrated a cell aut...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 2009
ISSN: 0884-0431,0884-0431
DOI: 10.1359/jbmr.090502